Structure Therapeutics Inc. American Depositary Shares (GPCR · NASDAQ)
GPCR · MARKET VIEW
Market view · as of Oct 12, 2026
Price (last ~year)
Structure Therapeutics (GPCR) fell to a 52-week low of $25.56, down 33.9% over the past month and 44.5% over three months, leaving shares 72.8% below their 52-week high. The clinical-stage biopharmaceutical company, which has no revenue, posted a Q2 net loss of $106.2M on operating expenses of $118.6M, widening from a $76.2M net loss in Q1, and missed EPS estimates in three of its last four quarters. The balance sheet remains liquid, with $272.6M in cash, minimal debt of $6.2M, and a current ratio of 20.75, against a market cap of $1.82B. The analyst target stands at $105.78, though the stock's RSI of 1 and trading at 0.4x average volume underscore deeply oversold conditions.
Valuation
- Market cap
- $1.82B
- P/B
- 1.893
- EV/EBITDA
- -13.46
- Beta
- -1.368
- Analyst target
- $105.78
Quality & returns
- Operating margin
- 0.0%
- Profit margin
- 0.0%
- ROE
- -20.2%
- ROA
- -14.9%
Price movement
- Last
- $25.54
- 1-month
- -33.9%
- 3-month
- -44.5%
- RSI (14)
- 1
- vs SMA200
- -51.5%
- 52-wk position
- 0.0% -72.8% vs high
Quarterly trajectory
Revenue by quarter (oldest → newest)
| Quarter | Revenue | Op income | Net income | EBITDA |
|---|---|---|---|---|
| 2026-06-30 | $0 | $-118.6M | $-106.2M | $-105.4M |
| 2026-03-31 | $0 | $-89.6M | $-76.2M | $-75.4M |
| 2025-12-31 | $0 | $24.0M | $33.0M | $33.6M |
| 2025-09-30 | $0 | $-73.8M | $-65.7M | $-65.2M |
Recent news
- Somewhat-Bullish Structure Therapeutics stock hits 52-week low at 25.56 USD By Investing.com · 2026-10-08
- Somewhat-Bullish Structure Therapeutics stock hits 52-week low at 25.56 USD By Investing.com · 2026-10-08
- Bullish We Think Structure Therapeutics (NASDAQ:GPCR) Can Afford To Drive Business Growth · 2026-09-30
- Neutral Structure Therapeutics Inc. (GPCR) Stock Price, News, Quote & History · 2026-09-24
- Somewhat-Bearish Structure Therapeutics (GPCR) CMO sells shares under preset plan · 2026-09-22
- Somewhat-Bullish Form 144 Structure Therapeutics Inc. For: 22 September By Investing.com · 2026-09-22
Sources this view read
- fundamentals Company overview & valuation (Alpha Vantage OVERVIEW)
- filing Quarterly financial statements (Alpha Vantage INCOME/BALANCE/CASH)
- earnings Reported earnings history (Alpha Vantage EARNINGS)
- prices Adjusted daily prices (Alpha Vantage TIME_SERIES_DAILY_ADJUSTED)