Structure Therapeutics Inc. American Depositary Shares (GPCR · NASDAQ)

GPCR · MARKET VIEW

Market view · as of Sep 28, 2026

Revenue (TTM)
$0
0.0% YoY
EPS (latest q)
$-0.49
vs $-0.39 est · miss
52-wk position
15.9%
-61.7% vs 52w high · -27.0% 1mo

Price (last ~year)

Structure Therapeutics (GPCR, NASDAQ) has fallen sharply over the past three months — down 31.1%, including a 27.0% decline in the last month — with the stock at $35.93, an RSI of 18, and trading 34.0% below its 200-day SMA. The clinical-stage biotech, which is developing oral therapeutics for chronic diseases including obesity, generated no revenue in the trailing twelve months and posted a Q2 net loss of $106.2M, wider than the prior quarter's $76.2M, while missing EPS estimates in each of its last four reports. Liquidity remains substantial, with $272.6M in cash, minimal debt of $6.2M, and a current ratio of 20.75, against a quarterly free cash outflow of $120.2M. The company's market cap stands at $2.56B, with an analyst target of $105.78, and recent news flow has centered on a CMO's planned sale of 4,008 shares (~$140K) under a Rule 10b5-1 plan.

Valuation

Market cap
$2.56B
P/B
1.893
EV/EBITDA
-13.46
Beta
-1.521
Analyst target
$105.78

Quality & returns

Operating margin
0.0%
Profit margin
0.0%
ROE
-20.2%
ROA
-14.9%

Price movement

Last
$35.93
1-month
-27.0%
3-month
-31.1%
RSI (14)
18
vs SMA200
-34.0%
52-wk position
15.9% -61.7% vs high

Quarterly trajectory

Revenue by quarter (oldest → newest)

QuarterRevenueOp incomeNet incomeEBITDA
2026-06-30$0$-118.6M$-106.2M$-105.9M
2026-03-31$0$-89.6M$-76.2M$-74.8M
2025-12-31$0$24.0M$33.0M$33.6M
2025-09-30$0$-73.8M$-65.7M$-65.3M

Recent news

Sources this view read

  • fundamentals Company overview & valuation (Alpha Vantage OVERVIEW)
  • filing Quarterly financial statements (Alpha Vantage INCOME/BALANCE/CASH)
  • earnings Reported earnings history (Alpha Vantage EARNINGS)
  • prices Adjusted daily prices (Alpha Vantage TIME_SERIES_DAILY_ADJUSTED)

Other snapshots