Structure Therapeutics Inc. American Depositary Shares (GPCR · NASDAQ)
GPCR · MARKET VIEW
Market view · as of Sep 28, 2026
Price (last ~year)
Structure Therapeutics (GPCR, NASDAQ) has fallen sharply over the past three months — down 31.1%, including a 27.0% decline in the last month — with the stock at $35.93, an RSI of 18, and trading 34.0% below its 200-day SMA. The clinical-stage biotech, which is developing oral therapeutics for chronic diseases including obesity, generated no revenue in the trailing twelve months and posted a Q2 net loss of $106.2M, wider than the prior quarter's $76.2M, while missing EPS estimates in each of its last four reports. Liquidity remains substantial, with $272.6M in cash, minimal debt of $6.2M, and a current ratio of 20.75, against a quarterly free cash outflow of $120.2M. The company's market cap stands at $2.56B, with an analyst target of $105.78, and recent news flow has centered on a CMO's planned sale of 4,008 shares (~$140K) under a Rule 10b5-1 plan.
Valuation
- Market cap
- $2.56B
- P/B
- 1.893
- EV/EBITDA
- -13.46
- Beta
- -1.521
- Analyst target
- $105.78
Quality & returns
- Operating margin
- 0.0%
- Profit margin
- 0.0%
- ROE
- -20.2%
- ROA
- -14.9%
Price movement
- Last
- $35.93
- 1-month
- -27.0%
- 3-month
- -31.1%
- RSI (14)
- 18
- vs SMA200
- -34.0%
- 52-wk position
- 15.9% -61.7% vs high
Quarterly trajectory
Revenue by quarter (oldest → newest)
| Quarter | Revenue | Op income | Net income | EBITDA |
|---|---|---|---|---|
| 2026-06-30 | $0 | $-118.6M | $-106.2M | $-105.9M |
| 2026-03-31 | $0 | $-89.6M | $-76.2M | $-74.8M |
| 2025-12-31 | $0 | $24.0M | $33.0M | $33.6M |
| 2025-09-30 | $0 | $-73.8M | $-65.7M | $-65.3M |
Recent news
- Neutral Structure Therapeutics Inc. (GPCR) Stock Price, News, Quote & History · 2026-09-24
- Somewhat-Bearish Structure Therapeutics (GPCR) CMO sells shares under preset plan · 2026-09-22
- Somewhat-Bullish Form 144 Structure Therapeutics Inc. For: 22 September By Investing.com · 2026-09-22
- Somewhat-Bearish Planned $140K share sale by Structure Therapeutics (Nasdaq: GPCR) officer · 2026-09-21
- Somewhat-Bullish (GPCR) Movement as an Input in Quant Signal Sets · 2026-09-21
- Neutral Structure Therapeutics Inc. - American Depositary Shares (Nasdaq:GPCR) Price Chart · 2026-09-17
Sources this view read
- fundamentals Company overview & valuation (Alpha Vantage OVERVIEW)
- filing Quarterly financial statements (Alpha Vantage INCOME/BALANCE/CASH)
- earnings Reported earnings history (Alpha Vantage EARNINGS)
- prices Adjusted daily prices (Alpha Vantage TIME_SERIES_DAILY_ADJUSTED)