Structure Therapeutics Inc. American Depositary Shares (GPCR · NASDAQ)
GPCR · MARKET VIEW
Market view · as of Oct 5, 2026
Price (last ~year)
Structure Therapeutics (GPCR) has fallen sharply, down 41.6% over the past month and 49.8% over three months to $27.67, leaving shares 70.5% below their 52-week high with an RSI of 16. The clinical-stage biotech generated no revenue in the trailing twelve months and posted a quarterly net loss of $106.2 million as of June 30, though it holds $272.6 million in cash against just $6.2 million of debt and a current ratio of 20.75. The company missed analyst EPS estimates in three of its last four quarters, including a June-quarter loss of $0.49 versus a $0.39 estimate. The analyst target stands at $105.78, and recent commentary has focused on the company's cash runway to fund ongoing operations.
Valuation
- Market cap
- $1.97B
- P/B
- 1.893
- EV/EBITDA
- -13.46
- Beta
- -1.521
- Analyst target
- $105.78
Quality & returns
- Operating margin
- 0.0%
- Profit margin
- 0.0%
- ROE
- -20.2%
- ROA
- -14.9%
Price movement
- Last
- $27.67
- 1-month
- -41.6%
- 3-month
- -49.8%
- RSI (14)
- 16
- vs SMA200
- -48.3%
- 52-wk position
- 1.9% -70.5% vs high
Quarterly trajectory
Revenue by quarter (oldest → newest)
| Quarter | Revenue | Op income | Net income | EBITDA |
|---|---|---|---|---|
| 2026-06-30 | $0 | $-118.6M | $-106.2M | $-105.9M |
| 2026-03-31 | $0 | $-89.6M | $-76.2M | $-74.8M |
| 2025-12-31 | $0 | $24.0M | $33.0M | $33.6M |
| 2025-09-30 | $0 | $-73.8M | $-65.7M | $-65.3M |
Recent news
- Bullish We Think Structure Therapeutics (NASDAQ:GPCR) Can Afford To Drive Business Growth · 2026-09-30
- Neutral Structure Therapeutics Inc. (GPCR) Stock Price, News, Quote & History · 2026-09-24
- Somewhat-Bearish Structure Therapeutics (GPCR) CMO sells shares under preset plan · 2026-09-22
- Somewhat-Bullish Form 144 Structure Therapeutics Inc. For: 22 September By Investing.com · 2026-09-22
- Somewhat-Bearish Planned $140K share sale by Structure Therapeutics (Nasdaq: GPCR) officer · 2026-09-21
- Somewhat-Bullish (GPCR) Movement as an Input in Quant Signal Sets · 2026-09-21
Sources this view read
- fundamentals Company overview & valuation (Alpha Vantage OVERVIEW)
- filing Quarterly financial statements (Alpha Vantage INCOME/BALANCE/CASH)
- earnings Reported earnings history (Alpha Vantage EARNINGS)
- prices Adjusted daily prices (Alpha Vantage TIME_SERIES_DAILY_ADJUSTED)