Structure Therapeutics Inc. American Depositary Shares (GPCR · NASDAQ)
GPCR · MARKET VIEW
Market view · as of Sep 7, 2026
Revenue (TTM)
$0
0.0% YoY
EPS (latest q)
$-0.49
vs $-0.39 est · miss
52-wk position
36.9%
-49.5% vs 52w high · -10.9% 1mo
Price (last ~year)
Structure Therapeutics (GPCR) is advancing its oral GLP-1 candidate, aleniglipron, to Phase 3 development following Phase 2b results showing 16.2% weight loss. The clinical-stage biopharmaceutical company holds a $3.38 billion market capitalization with $272.6 million in cash and $6.2 million in debt as of June 30, 2026. Financial results for the second quarter reflect $0 revenue and a net loss of $106.2 million. Shares closed at $47.34, down 10.9% over the past month.
Valuation
- Market cap
- $3.38B
- P/B
- 2.499
- EV/EBITDA
- -13.46
- Beta
- -1.521
- Analyst target
- $104.77
Quality & returns
- Operating margin
- 0.0%
- Profit margin
- 0.0%
- ROE
- -20.2%
- ROA
- -14.9%
Price movement
- Last
- $47.34
- 1-month
- -10.9%
- 3-month
- +14.0%
- RSI (14)
- 26
- vs SMA200
- -12.9%
- 52-wk position
- 36.9% -49.5% vs high
Quarterly trajectory
Revenue by quarter (oldest → newest)
| Quarter | Revenue | Op income | Net income | EBITDA |
|---|---|---|---|---|
| 2026-06-30 | $0 | $-118.6M | $-106.2M | $-105.9M |
| 2026-03-31 | $0 | $-89.6M | $-76.2M | $-74.8M |
| 2025-12-31 | $0 | $24.0M | $33.0M | $33.6M |
| 2025-09-30 | $0 | $-73.8M | $-65.7M | $-65.3M |
Recent news
- Somewhat-Bullish Structure Therapeutics to Participate in Upcoming Healthcare Investor Conferences · 2026-09-03
- Somewhat-Bullish (GPCR) Movement Within Algorithmic Entry Frameworks · 2026-09-01
- Somewhat-Bullish NVO vs. GPCR: Which Obesity Stock Is the Better Buy Right Now? · 2026-08-26
- Bullish Structure Therapeutics' oral GLP-1 drug shows 16.2% weight loss, advancing to Phase 3 with strong cash backing. · 2026-08-22
- Somewhat-Bearish Structure Therapeutics can't force chief financial officer’s harassment claim into arbitration · 2026-08-20
- Somewhat-Bullish Handelsbanken Fonder AB Purchases Shares of 19,400 Structure Therapeutics Inc. Sponsored ADR $GPCR · 2026-08-20
Sources this view read
- fundamentals Company overview & valuation (Alpha Vantage OVERVIEW)
- filing Quarterly financial statements (Alpha Vantage INCOME/BALANCE/CASH)
- earnings Reported earnings history (Alpha Vantage EARNINGS)
- prices Adjusted daily prices (Alpha Vantage TIME_SERIES_DAILY_ADJUSTED)